Doublecortin Rabbit pAb(A0149)

Catalog No.	A0149
Product Name	Doublecortin Rabbit pAb(A0149)
Supplier Name	Caprico Biotechnologies, Inc.
Brand Name	Caprico
Synonyms	DC; DBCN; LISX; SCLH; XLIS
Gene Name	DCX
Protein Name	DCX
Uniprot ID	O43602
Clonality	Polyclonal
Source/Host	Rabbit
Applications	WB, IF/ICC
Reactivity	Human, Mouse
Conjugate	Unconjugated
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Description

A0149：Doublecortin Rabbit pAb(A0149)

This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, cognitive disability, subcortical band heterotopia (“double cortex” syndrome) in females and lissencephaly (“smooth brain” syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene.
Please remember our product information: Doublecortin Rabbit pAb(A0149) catalog number: A0149 Caprico Biotechnologies

Additional information

Ship from Country	USA
Size	100 μL

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