MGMT Polyclonal Antibody
$350.00
Conditions of optimal MGMT polyclonal antibody performance should be determined experimentally by the investigator.
SKU: PA002338-PA1408
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| Catalog No. | PA002338-PA1408 |
|---|---|
| Product Name | MGMT Polyclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | 6-O- methylguanine-DNA methyltransferase, EC 2.1.1.63, MGMT, Methylated-DNA-protein-cysteine methyltransferase |
| Isotype | Rabbit IgG. |
| Specificity/Sensitivity | Human, Mouse, Rat. No cross reactivity with other proteins. |
| Reactivity | Human, Mouse, Rat. |
| Immunogen | A synthetic peptide corresponding to a sequence at the middle region of human MGMT, different from the related mouse sequence by one amino acid. |
| Purification | Immunogen affinity purified. |
| Form Of Antibody | Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. |
| Stability & Storage | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Note | Conditions of optimal MGMT antibody performance should be determined experimentally by the investigator. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PA002338-PA1408: MGMT Polyclonal Antibody
Introduction
Methylated-DNA-protein-cysteine methytransferase (MGMT) is an enzyme that in humans is encoded by the MGMT gene. O(6)-alkylguanine is the major mutagenic and carcinogenic lesion in DNA induced by simple alkylating mutagens. MGMT gene is mapped to chromosome 10. Rydberg et al. (1990) concluded that the methyltransferase gene spans at least 15 kb. Gardner et al. (1991) refined the localization of the gene to 10q24.33-qter. Methylation of the gene’s promoter plays a significant role in carcinogenesis.
Other MGMT Antibody:
MGMT Polyclonal Antibody
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug |
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