MCM4 Polyclonal Antibody

MCM4 Polyclonal Antibody

$350.00

In stock

$350.00

Conditions of optimal MCM4 polyclonal antibody performance should be determined experimentally by the investigator.

SKU: PA002300-PA1652
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Catalog No. PA002300-PA1652
Product NameMCM4 Polyclonal Antibody
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Synonyms CDC21 homolog, DNA replication licensing factor MCM4, P1-CDC21
Isotype Rabbit IgG.
Reactivity Human, Rat, Mouse.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminal of human MCM4,identical to the related rat and mouse sequences.
Purification Immunogen affinity purified.
Form Of Antibody Lyophilized.
Stability & Storage Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Note Conditions of optimal MCM4 antibody performance should be determined experimentally by the investigator.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

PA002300-PA1652: MCM4 Polyclonal Antibody
Introduction
MCM4(MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 4),also called CDC21, S. POMBE, HOMOLOG OF, is a protein that in humans is encoded by the MCM4 gene. MCM4 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The MCM4 gene is mapped to 8q11.21. The 864-amino acid MCM4 protein has an observed molecular mass of 97 kD by SDS-PAGE, which is similar to its calculated molecular mass of 96.6 kD. Western blot analysis with and without phosphatase treatment suggested that MCM4 is highly phosphorylated in mitotic cells. In the absence of DDK, CDK phosphorylation at the distal part of the Mcm4 NSD becomes crucial.MCM4 encodes a subunit of the MCM2-7 complex (also known as MCM2-MCM7), the replication licensing factor and presumptive replicative helicase.
Other MCM4 Antibody:
MCM4 (Ab-54) Polyclonal Antibody

Additional information

Ship from Country

USA

Size

100 ug

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