LAMC1 Polyclonal Antibody

LAMC1 Polyclonal Antibody

$350.00

In stock

$350.00

Conditions of optimal LAMC1 polyclonal antibody performance should be determined experimentally by the investigator.

SKU: PA002184-PA1581
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Catalog No. PA002184-PA1581
Product NameLAMC1 Polyclonal Antibody
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Synonyms Laminin subunit gamma-1 , Laminin B2 chain, LAMB2
Isotype Rabbit IgG.
Reactivity Human, Rat, Mouse.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminal of human Laminin ?1, different from the related mouse sequence by one amino acid and rat sequence by three amino acids.
Form Of Antibody Lyophilized.
Stability & Storage Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Note Conditions of optimal LAMC1 antibody performance should be determined experimentally by the investigator.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

PA002184-PA1581: LAMC1 Polyclonal Antibody
Introduction
Laminin ?1, Laminin subunit gamma-1, is a protein that in humans is encoded by the LAMC1 gene. Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 1.
Other LAMC1 Antibody:
LAMC1 Polyclonal Antibody

Additional information

Ship from Country

USA

Size

100 ug

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