[KO Validated] MTA2 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

[KO Validated] MTA2 Rabbit pAb

$128.00$548.00

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$128.00$548.00

PID; MTA1L1

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SKU: A2243
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Catalog No. A2243
Product Name[KO Validated] MTA2 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms PID; MTA1L1
Gene Name MTA2
Protein Name MTA2
Uniprot/Swissprot ID O94776
Entrez GeneID 9219
Clonality Polyclonal
Source/Host Rabbit
Applications WB, ChIP
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
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Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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