IPO7 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

IPO7 Rabbit pAb

$108.00$488.00

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$108.00$488.00

Imp7; RANBP7

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SKU: A18417
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Catalog No. A18417
Product NameIPO7 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms Imp7; RANBP7
Gene Name IPO7
Protein Name IPO7
Uniprot/Swissprot ID O95373
Entrez GeneID 10527
Clonality Polyclonal
Source/Host Rabbit
Applications WB, IF/ICC
Reactivity Human, Mouse, Rat
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The importin-alpha/beta complex and the GTPase Ran mediate nuclear import of proteins with a classical nuclear localization signal. The protein encoded by this gene is a member of a class of approximately 20 potential Ran targets that share a sequence motif related to the Ran-binding site of importin-beta. Similar to importin-beta, this protein prevents the activation of Ran’s GTPase by RanGAP1 and inhibits nucleotide exchange on RanGTP, and also binds directly to nuclear pore complexes where it competes for binding sites with importin-beta and transportin. This protein has a Ran-dependent transport cycle and it can cross the nuclear envelope rapidly and in both directions. At least four importin beta-like transport receptors, namely importin beta itself, transportin, RanBP5 and RanBP7, directly bind and import ribosomal proteins.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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