ESPL1 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

ESPL1 Rabbit pAb

$108.00$488.00

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$108.00$488.00

ESP1; SEPA

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SKU: A15366
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Catalog No. A15366
Product NameESPL1 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms ESP1; SEPA
Gene Name ESPL1
Protein Name ESPL1
Uniprot/Swissprot ID Q14674
Entrez GeneID 9700
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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