DCAMKL1/DCLK1 Rabbit pAb

Catalog No.	A9474
Product Name	DCAMKL1/DCLK1 Rabbit pAb
Supplier Name	ABclonal, Inc.
Brand Name	Abclonal
Synonyms	CL1; DCLK; CLICK1; DCDC3A; DCAMKL1
Gene Name	DCLK1
Protein Name	DCLK1
Uniprot/Swissprot ID	O15075
Entrez GeneID	9201
Clonality	Polyclonal
Source/Host	Rabbit
Applications	WB, IF/ICC
Reactivity	Human, Mouse, Rat
Conjugate	Unconjugated
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. The encoded protein is involved in several different cellular processes, including neuronal migration, retrograde transport, neuronal apoptosis and neurogenesis. This gene is up-regulated by brain-derived neurotrophic factor and associated with memory and general cognitive abilities. Multiple transcript variants generated by two alternative promoter usage and alternative splicing have been reported, but the full-length nature and biological validity of some variants have not been defined. These variants encode different isoforms, which are differentially expressed and have different kinase activities.

Additional information

Ship from Country	USA
Size	20 ul, 100 ul, 200 ul

No more offers for this product!