Daratumumab Biosimilar, Anti-human CD38 Monoclonal Antibody | C030P

Catalog No.	C030P
Product Name	Daratumumab Biosimilar, Anti-human CD38 Monoclonal Antibody | C030P
Supplier Name	Syd Labs, Inc.
Brand Name	Syd Labs
Synonyms	cluster of differentiation 38, cyclic ADP ribose hydrolase, a paralog of CD157, ADPRC1
Summary	Recombinant Humanized IgG1 Monoclonal Antibody.
Source/Host	The anti-human CD38 monoclonal antibody daratumumab biosimilar was produced in the daratumumab biosimilar CHO stable cell line.
Specificity/Sensitivity	The in vivo grade daratumumab biosimilar specifically binds to the human CD38 protein, causing cells to apoptose via antibody-dependent cellular cytotoxicity, complement-dependent cytotoxicity, inhibition of mitochondrial transfer or antibody-dependent cellular phagocytosis.
Applications	ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by daratumumab.
Form Of Antibody	0.2 uM filtered solution, pH 6.0, no stabilizers or preservatives.
Endotoxin	< 1 EU per 1 mg of the protein by the LAL method.
Purity	>95% by SDS-PAGE under reducing conditions and HPLC.
Shipping	The research grade daratumumab biosimilar is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
Note	The research grade Daratumumab biosimilar protein is for research use only (RUO). Recombinant human IgG1 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
Order Offline	Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card.

Description

C030P: Daratumumab Biosimilar, Anti-human CD38 Monoclonal Antibody

Recombinant Humanized IgG1 Monoclonal Antibody.

Background

Daratumumab Biosimilar uses the same protein sequences as the therapeutic antibody daratumumab.

Daratumumab (Anti-Human CD38) is the first-in-class human-specific anti-CD38 monoclonal antibody. Daratumumab has anti-multiple myeloma (MM) effect. Daratumumab impairs MM cell adhesion, which results in an increased sensitivity of MM to proteasome inhibition.

Syd Labs provides the following research grade anti-CD38 antibody biosimilars:
Isatuximab Biosimilar, research grade, anti-human CD38 monoclonal antibody

Please remember our product information: Daratumumab Biosimilar, CD38 Monoclonal Antibody: C030P Syd Labs

No more offers for this product!