CLDN18 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

CLDN18 Rabbit pAb

$108.00$488.00

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$108.00$488.00

SFTA5; SFTPJ

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SKU: A8392
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Catalog No. A8392
Product NameCLDN18 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms SFTA5; SFTPJ
Gene Name CLDN18
Protein Name CLDN18
Uniprot/Swissprot ID P56856
Entrez GeneID 51208
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.

Additional information

Ship from Country

USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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