Caspase-4 Rabbit pAb

Caspase-4 Rabbit pAb

$108.00$278.00

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$108.00$278.00

TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II

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SKU: A19305
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Catalog No. A19305
Product NameCaspase-4 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms TX; Mih1; ICH-2; Mih1/TX; ICEREL-II; ICE(rel)II
Gene Name CASP4
Protein Name CASP4
Uniprot/Swissprot ID P49662
Entrez GeneID 837
Clonality Polyclonal
Source/Host Rabbit
Applications WB, IHC-P
Reactivity Human
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

Additional information

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USA

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20 ul, 100 ul, 50 ul

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