Cadherin-pan Polyclonal Antibody

Cadherin-pan Polyclonal Antibody

$250.00$350.00

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$250.00$350.00

Conditions of optimal cadherin-pan polyclonal antibody performance should be determined experimentally by the investigator.

SKU: PA000978-C0148
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Catalog No. PA000978-C0148
Product NameCadherin-pan Polyclonal Antibody
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Synonyms CADH1, CAM 120/80, CDH1, cadherin-1, epithelial-cadherin, uvomorulin
Specificity/Sensitivity E-cadherin-pan antibody detects endogenous levels of total E-cadherin protein.
Reactivity Human, Mouse, Rat.
Immunogen The antiserum was produced against synthesized peptide derived from human E-cadherin.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form Of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Stability & Storage Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Note Conditions of optimal Cadherin-pan antibody performance should be determined experimentally by the investigator.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

PA000978-C0148: Cadherin-pan Polyclonal Antibody

Cadherins are calcium-dependent cell-cell adhesion molecules that mediate cell-cell binding in a homophilic manner. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherin expression is regulated spatially as well as temporally. Cadherins are thought to play an important role in development and maintenance of tissues through selective cell-cell adhesion activity and may be involved also in the invasion and metastasis of malignant tumors. Cadherin regulates dendritic spine morphogenesis. A cadherin gene cluster is mapped to a region of chromosome 5 subject to frequent allelic loss in carcinoma.

Additional information

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USA

Size

100 ug, 50 ug

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