c-PLA2 (Ab-505) Polyclonal Antibody
$250.00 – $350.00
Conditions of optimal c-PLA2 (Ab-505) polyclonal antibody performance should be determined experimentally by the investigator.
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| Catalog No. | PA001309-B0065 |
|---|---|
| Product Name | c-PLA2 (Ab-505) Polyclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | CPLA2, Cytosolic phospholipase A2, EC 3.1.1.4, EC 3.1.1.5, PA24, PA24A, PLA2G4, PLA2G4A, Phosphatidylcholine 2-acylhydrolase |
| Specificity/Sensitivity | c-PLA2 (Ab-505) antibody detects endogenous levels of total c-PLA2 protein. |
| Reactivity | Human, Mouse, Rat. |
| Immunogen | The antiserum was produced against synthesized non-phosphopeptide derived from human c-PLA2 around the phosphorylation site of serine 505 P(P-L-S -P-L). |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Form Of Antibody | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Stability & Storage | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Note | Conditions of optimal c-PLA2 antibody performance should be determined experimentally by the investigator. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PA001309-B0065: c-PLA2 (Ab-505) Polyclonal Antibody
Background
PLA2G4A (Phospholipase A2, Group IVA), is an enzyme that in humans is encoded by the PLA2G4A gene. Tay et al. (1995) mapped the PLA2G4A gene to rat chromosome 13 by PCR-based intercross genotyping and to human 1q25 by fluorescence in situ hybridization. By site-directed mutagenesis and biochemical analysis of the recombinant protein, Sharp et al. (1994) determined that ser228 participates in the catalytic mechanism of cPLA2 and that both the phospholipase A2 and the lysophospholipase activities are catalyzed by the same active site residue(s). PLA2G4A, the cytosolic phospholipase A2, appears to subserve transmembrane signaling responses to extracellular ligands (Skorecki, 1995).
Other c-PLA2 Antibody:
c-PLA2 Polyclonal Antibody
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 50 ug |
