BUB1 Polyclonal Antibody
$250.00 – $350.00
Conditions of optimal BUB1 polyclonal antibody performance should be determined experimentally by the investigator.
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| Catalog No. | PA000944-R12-2550 |
|---|---|
| Product Name | BUB1 Polyclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | BUB1A, BUB1L, EC 2.7.11.1, MBUB1, Mitotic checkpoint BUB1, hBUB1 |
| Specificity/Sensitivity | BUB1 antibody detects endogenous levels of BUB1. |
| Reactivity | Human. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human BUB1. |
| Purification | The antibody was affinity-purified from rabbit anti-serum by immunogenic peptide affinity-chromatography. |
| Form Of Antibody | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Stability & Storage | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Note | Conditions of optimal BUB1 antibody performance should be determined experimentally by the investigator. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PA000944-R12-2550: BUB1 Polyclonal Antibody
Introduction
Mitotic checkpoint serine/threonine-protein kinase BUB1 also known as BUB1 (budding uninhibited by benzimidazoles 1) is an enzyme that in humans is encoded by the BUB1 gene. Bub1 is a serine/threonine protein kinase first identified in genetic screens of Saccharomyces cerevisiae. The protein is bound to kinetochores and plays a key role in the establishment of the mitotic spindle checkpoint and chromosome congression. The mitotic checkpoint kinase is evolutionary conserved in organisms as diverse as Saccharomyces cerevisiae and humans. Loss-of-function mutations or absence of Bub1 has been reported to result in aneuploidy, chromosomal instability (CIN) and premature senescence.
Other BUB1 Antibody:
BUB1 Polyclonal Antibody
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 50 ug |
