ABflo® 488 Rabbit anti-Human/Mouse PDGFRα/CD140a mAb (A22689)

ABflo® 488 Rabbit anti-Human/Mouse PDGFRα/CD140a mAb (A22689)

ABflo® 488 Rabbit anti-Human/Mouse PDGFRα/CD140a mAb (A22689)

$290.00$768.00

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$290.00$768.00

Abclonal ABflo® 488 Rabbit anti-Human/Mouse PDGFRα/CD140a mAb (Catalog Number: A22689) encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin.

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Catalog No. A22689
Product NameABflo® 488 Rabbit anti-Human/Mouse PDGFRα/CD140a mAb (A22689)
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms CD140A; PDGFR2; PDGFR-2
Gene Name PDGFRA
Protein Name PDGFRA
Uniprot/Swissprot ID P16234
Entrez GeneID 5156
Clonality Monoclonal
Source/Host Rabbit
Applications FC
Reactivity Mouse
Conjugate ABflo® 488. Ex:491nm. Em:516nm.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

A22689: ABflo® 488 Rabbit anti-Human/Mouse PDGFRα/CD140a mAb

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Immunogen Information about ABflo® 488 Rabbit anti-Human/Mouse PDGFRα/CD140a mAb (A22689)

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 24-524 of human PDGFRα (NP_006197.1).
Sequence:QLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYPMSEEESSDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTCYYNHTQTEENELEGRHIYIYVPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLHNSEGVVPASYDSRQGFNGTFTVGPYICEATVKGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNNEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATREVKEMKKVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVRAYPPPRISWLKNNLTLIENLTEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIVAQNEDAVKSYTFELLTQVPSSILDLVDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTILANNVSNIITEIHSRDRSTVEGRVTFAKVEETIAVRCLAKNLLGAENRELKLVAPTLRSE
Gene ID:5156
Swiss prot:P16234
Synonyms:CD140A; PDGFR2; PDGFR-2
Calculated MW:24kDa/82kDa/123kDa
Observed MW:Refer to figures

Images of ABflo® 488 Rabbit anti-Human/Mouse PDGFRα/CD140a mAb (A22689)

Flow cytometry:1X10^6 HeLa cells (negative control, Left) and U-138 MG cells (Right) were surface-stained with ABflo® 488 Rabbit anti-Mouse PDGFRα/CD140a mAb (A22689, 5 μl/Test, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).

Flow cytometry: 1X10^6 NIH/3T3 cells were surface-stained with ABflo® 488 Rabbit anti-Mouse PDGFRα/CD140a mAb (A22689, 5 μl/Test, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line).Non-fluorescently stained NIH/3T3 cells were used as blank control (red line).

Flow cytometry:1X10^6 U-138 MG cells were surface-stained with ABflo™ 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo™ 488 Rabbit anti-Human/Mouse PDGFRα/CD140a mAb (A22689, 5 μl/Test, right).

Flow cytometry:1X10^6 NIH/3T3 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo® 488 Rabbit anti-Mouse PDGFRα/CD140a mAb (A22689, 5 μl/Test, right).

Please remember our product information: ABflo® 488 Rabbit anti-Human/Mouse PDGFRα/CD140a mAb (Catalog Number: A22689) Abclonal

Additional information

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USA

Size

100 μg, 25 μg, 50 μg

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