TGF beta 1 Rabbit pAb
$108.00 – $488.00
CED; LAP; DPD1; TGFB; IBDIMDE; TGFbeta; TGF-beta1
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| Catalog No. | A15103 |
|---|---|
| Product Name | TGF beta 1 Rabbit pAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | CED; LAP; DPD1; TGFB; IBDIMDE; TGFbeta; TGF-beta1 |
| Gene Name | TGFB1 |
| Protein Name | TGFB1 |
| Uniprot/Swissprot ID | P01137 |
| Entrez GeneID | 7040 |
| Clonality | Polyclonal |
| Source/Host | Rabbit |
| Applications | IF/ICC |
| Reactivity | Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 20 ul, 100 ul, 200 ul, 50 ul |