TCL1A Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

TCL1A Rabbit pAb

$108.00$488.00

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$108.00$488.00

TCL1

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SKU: A0629
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Catalog No. A0629
Product NameTCL1A Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms TCL1
Gene Name TCL1A
Protein Name TCL1A
Uniprot/Swissprot ID P56279
Entrez GeneID 8115
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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