TBP Polyclonal Antibody

Catalog No.	PA003493-PA1534
Product Name	TBP Polyclonal Antibody
Supplier Name	Syd Labs, Inc.
Brand Name	Syd Labs
Synonyms	TATA binding factor, TATA sequence-binding protein, TATA-box binding protein, TATA-box factor, TFIID
Isotype	Rabbit IgG.
Reactivity	Human, Mouse, Rat.
Immunogen	A synthetic peptide corresponding to a sequence in the middle region of human TBP, identical to the related rat and mouse sequences.
Purification	Immunogen affinity purified.
Form Of Antibody	Lyophilized.
Stability & Storage	Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Note	Conditions of optimal TBP antibody performance should be determined experimentally by the investigator.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

PA003493-PA1534: TBP Polyclonal Antibody
Introduction
TBP, TATA-binding protein, is a general transcription factor that binds specifically to a DNA sequence called the TATA box. The TBP gene is mapped to 6q27. This DNA sequence is found about 35 base pairs upstream of the transcription start site in some eukaryotic gene promoters. TBP, along with a variety of TBP-associated factors, make up the TFIID, a general transcription factor that in turn makes up part of the RNA polymerase II preinitiation complex. As one of the few proteins in the preinitiation complex that binds DNA in a sequence-specific manner, it helps position RNA polymerase II over the transcription start site of the gene. However, it is estimated that only 10-20% of human promoters have TATA boxes. Therefore, TBP is probably not the only protein involved in positioning RNA polymerase II.
Other TBP Antibody:
TBP Polyclonal Antibody

Additional information

Ship from Country	USA
Size	100 ug

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