STRADA Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

STRADA Rabbit pAb

$108.00$488.00

In stock

$108.00$488.00

LYK5; PMSE; Stlk; STRAD; NY-BR-96; STRAD alpha

Store
SKU: A21707
Clear
View cart
Catalog No. A21707
Product NameSTRADA Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms LYK5; PMSE; Stlk; STRAD; NY-BR-96; STRAD alpha
Gene Name STRADA
Protein Name STRADA
Uniprot/Swissprot ID Q7RTN6
Entrez GeneID 92335
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene contains a STE20-like kinase domain, but lacks several residues that are critical for catalytic activity, so it is termed a ‘pseudokinase’. The protein forms a heterotrimeric complex with serine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39, also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11 from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has been shown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their full-length nature is not known.

Additional information

Ship from Country

USA

Size

20 ul, 100 ul, 200 ul, 50 ul

No more offers for this product!