RANBP2 Rabbit pAb
$108.00 – $488.00
ANE1; TRP1; TRP2; ADANE; IIAE3; NUP358
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- Description
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| Catalog No. | A18596 |
|---|---|
| Product Name | RANBP2 Rabbit pAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | ANE1; TRP1; TRP2; ADANE; IIAE3; NUP358 |
| Gene Name | RANBP2 |
| Protein Name | RANBP2 |
| Uniprot/Swissprot ID | P49792 |
| Entrez GeneID | 5903 |
| Clonality | Polyclonal |
| Source/Host | Rabbit |
| Applications | WB, IHC-P |
| Reactivity | Mouse, Rat |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
RAN is a small GTP-binding protein of the RAS superfamily that is associated with the nuclear membrane and is thought to control a variety of cellular functions through its interactions with other proteins. This gene encodes a very large RAN-binding protein that immunolocalizes to the nuclear pore complex. The protein is a giant scaffold and mosaic cyclophilin-related nucleoporin implicated in the Ran-GTPase cycle. The encoded protein directly interacts with the E2 enzyme UBC9 and strongly enhances SUMO1 transfer from UBC9 to the SUMO1 target SP100. These findings place sumoylation at the cytoplasmic filaments of the nuclear pore complex and suggest that, for some substrates, modification and nuclear import are linked events. This gene is partially duplicated in a gene cluster that lies in a hot spot for recombination on chromosome 2q.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 20 ul, 100 ul, 200 ul, 50 ul |