PRNP Polyclonal Antibody

Catalog No.	PA006668-PA1794
Product Name	PRNP Polyclonal Antibody
Supplier Name	Syd Labs, Inc.
Brand Name	Syd Labs
Synonyms	CD230, PRP
Isotype	Rabbit IgG.
Reactivity	Human.
Immunogen	A synthetic peptide corresponding to a sequence in the middle region of human PRNP.
Purification	Immunogen affinity purified.
Form Of Antibody	Lyophilized.
Stability & Storage	Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Note	Conditions of optimal PRNP Antibody performance should be determined experimentally by the investigator.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

PA006668-PA1794: PRNP Polyclonal Antibody
Introduction
PRNP(prion protein), also known as CD230 and PRP, is a protein that in humans is encoded by the PRNP gene. The major prion protein is expressed in the brain and several other tissues. Expression is most predominant in the nervous system but occurs in many other tissues throughout the body. Puckett et al. (1991)identified a RFLP with a high degree of heterozygosity in the 5-prime region of the PRNP gene, which might serve as a useful marker for the pter-p12 region of chromosome 20.PRNP is associated with a variety of cognitive deficiencies and neurodegenerative diseases such as Creutzfeldt-Jakob disease, bovine spongiform encephalopathy, and kuru. PRNP is highly conserved through mammals, lending credence to application of conclusions from test animals such as mice. Comparison between primates is especially similar, ranging from 92.9-99.6% similarity in amino acid sequences.
Other PRNP Antibody:
PRNP Polyclonal Antibody

Additional information

Ship from Country	USA
Size	100 ug

No more offers for this product!