PMVK Polyclonal Antibody
$350.00
Conditions of optimal PMVK polyclonal antibody performance should be determined experimentally by the investigator.
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| Catalog No. | PA000227-PA1067 |
|---|---|
| Product Name | PMVK Polyclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | Phosphomevalonate kinase Antibody |
| Isotype | Rabbit IgG. |
| Specificity/Sensitivity | Human, mouse, rat. No cross reactivity with other proteins. |
| Reactivity | Human, Mouse, Rat. |
| Immunogen | A synthetic peptide corresponding to a sequence mapping at the middle region of human PMVK, different from the related mouse and rat sequence by single amino acid. |
| Purification | Immunogen affinity purified. |
| Form Of Antibody | Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. |
| Stability & Storage | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Note | Conditions of optimal PMVK antibody performance should be determined experimentally by the investigator. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PA000227-PA1067: PMVK Polyclonal Antibody
Background
PMVK (phosphomevalonate kinase) is a cytosolic enzyme that catalyzes the conversion of mevalonate-5-phosphate to mevalonate-5-diphosphate. It is mapped to chromosome 1p13-1q22-23 and spans more than 8.4 kb in the human genome. PMVK is a peroxisomal protein which requires the C-terminal peroxisomal targeting signal, Ser-Arg-Leu, for localization to the organelle. It was expressed highly in heart, liver, skeletal muscle, kidney and pancreas and slightly lower in brain, placenta, and lung. And PMKase gene expression is subject to regulation by sterol at the level of transcription. It is a single copy gene covering less than 15 kb in the human genome. The human PMKase amino acid sequence contains a consensus peroxisomal targeting sequence (PTS-1), Ser-Arg-Leu, at the C terminus of the protein.
PMVK Enzymes:
Recombinant Human PMVK Enzyme
PMVK Polyclonal Antibody
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug |
