PKCA Polyclonal Antibody
$250.00 – $350.00
Conditions of optimal PKCA polyclonal antibody performance should be determined experimentally by the investigator.
- Product Details
- Description
- Additional information
- More Offers
| Catalog No. | PA000229-R12-3330 |
|---|---|
| Product Name | PKCA Polyclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | Protein Kinase C alpha Antibody |
| Specificity/Sensitivity | PKCα Antibody detects endogenous levels of PKCα. |
| Reactivity | Human, Mouse, Rat. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human PKCα. |
| Purification | The antibody was affinity-purified from rabbit anti-serum by immunogenic peptide affinity-chromatography. |
| Form Of Antibody | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Stability & Storage | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Note | Conditions of optimal PKCα antibody performance should be determined experimentally by the investigator. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PA000229-R12-3330: PKCA Polyclonal Antibody
Background
Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (?, ?I, ?II and?) and novel (n) PKC isoforms (?,?,?,?and?). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC and are independent of Ca2+ On the other hand, nPKC and , as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.
Other PKC alpha Antibodys:
PKCα Polyclonal Antibody
PKC alpha Enzyme:
Recombinant Human PKCα
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 50 ug |
