Phospho-CDK6-Y24 Rabbit pAb
$218.00 – $548.00
MCPH12; PLSTIRE
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| Catalog No. | AP0289 |
|---|---|
| Product Name | Phospho-CDK6-Y24 Rabbit pAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | MCPH12; PLSTIRE |
| Gene Name | CDK6 |
| Protein Name | CDK6 |
| Uniprot/Swissprot ID | Q00534 |
| Entrez GeneID | 1021 |
| Clonality | Polyclonal |
| Source/Host | Rabbit |
| Applications | WB, IF/ICC |
| Reactivity | Human, Mouse |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
The protein encoded by this gene is a member of the CMGC family of serine/threonine protein kinases. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Altered expression of this gene has been observed in multiple human cancers. A mutation in this gene resulting in reduced cell proliferation, and impaired cell motility and polarity, and has been identified in patients with primary microcephaly.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ul, 200 ul, 50 ul |