NTCP Polyclonal Antibody
$350.00
Conditions of optimal NTCP polyclonal antibody performance should be determined experimentally by the investigator.
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| Catalog No. | PA000161-PA1238 |
|---|---|
| Product Name | NTCP Polyclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | Na+-taurocholate cotransporting polypeptide Antibody |
| Isotype | Rabbit IgG. |
| Specificity/Sensitivity | Human, rat, mouse. No cross reactivity with other proteins. |
| Reactivity | Human, Mouse, Rat. |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminal of human NTCP, identical to the related rat and mouse sequence. |
| Purification | Immunogen affinity purified. |
| Form Of Antibody | Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3. |
| Stability & Storage | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Note | Conditions of optimal NTCP antibody performance should be determined experimentally by the investigator. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PA000161-PA1238: NTCP Polyclonal Antibody
Background
Na+-taurocholate cotransporting polypeptide (NTCP), also known as SLC10A1 (Solute carrier family 10,member 1) is the major bile acid uptake system in human hepatocytes. NTCP and the ileal transporter ASBT (apical sodium-dependent bile acid transporter) are two sodium-dependent transporters critical for the enterohepatic circulation of bile acids. The hASBT gene is known to be activated by the glucocorticoid receptor (GR).1 Ho RH et al. indicates functionally important polymorphisms in NTCP exist and that the likelihood of being carriers of such polymorphisms is dependent on ethnicity.2
Other NTCP Antibodies:
NTCP Polyclonal Antibody
NTCP Polyclonal Antibody
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug |
