NOX1 Polyclonal Antibody
$350.00
Conditions of optimal NOX1 polyclonal antibody performance should be determined experimentally by the investigator.
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| Catalog No. | PA006639-PA1666 |
|---|---|
| Product Name | NOX1 Polyclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | NOH1, MOX1 or GP91-2 |
| Isotype | Rabbit IgG. |
| Reactivity | Rat, Mouse. |
| Immunogen | A synthetic peptide corresponding to a sequence in the middle of rat NOX1, different from the related mouse sequence by one amino acid. |
| Purification | Immunogen affinity purified. |
| Form Of Antibody | Lyophilized. |
| Stability & Storage | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Note | Conditions of optimal NOX1 antibody performance should be determined experimentally by the investigator. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PA006639-PA1666: NOX1 Polyclonal Antibody
Introduction
NOX1(NADPH OXIDASE 1),also known as NOH1, MOX1 or GP91-2, is an enzyme that in humans is encoded by the NOX1 gene. It is also a homolog of the catalytic subunit of the superoxide-generating NADPH oxidase of phagocytes, gp91phox.The NOX1 gene is mapped to Xq22.1. NOX1 was expressed in colon, prostate, uterus, and vascular smooth muscle, but not in peripheral blood leukocytes. The deduced 564-amino acid NOX1 protein, which is 58% identical to CYBB, contains 6 membrane-spanning regions, conserved flavin and pyridine nucleotide-binding sites, and histidines possibly involved in heme ligation. Overexpression of MOX1 in NIH 3T3 cells increased superoxide generation and cell growth. Cells expressing MOX1 had a transformed appearance, showed anchorage-independent growth, and produced tumors in athymic mice. Disruption of either Nox1 or Nox2 significantly delayed progression of motor neuron disease in these mice. However, 50% survival rates were enhanced significantly more by Nox2 deletion than Nox1 deletion.
Other NOX1 Antibodies:
NOX1 Polyclonal Antibody
NOX1 Polyclonal Antibody
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug |
