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Catalog No. | A1390 |
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Product Name | MICA Rabbit pAb |
Supplier Name | ABclonal, Inc. |
Brand Name | Abclonal |
Synonyms | MIC-A; PERB11.1 |
Gene Name | MICA |
Protein Name | MICA |
Uniprot/Swissprot ID | Q29983 |
Entrez GeneID | 100507436 |
Clonality | Polyclonal |
Source/Host | Rabbit |
Applications | WB |
Reactivity | Human, Mouse, Rat |
Conjugate | Unconjugated |
Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing of this gene results in multiple transcript variants.
Additional information
Ship from Country | USA |
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Size | 20 ul, 100 ul, 200 ul, 50 ul |