MCP-1 Polyclonal Antibody

MCP-1 Polyclonal Antibody

$350.00

In stock

$350.00

Conditions of optimal MCP-1 polyclonal antibody performance should be determined experimentally by the investigator.

SKU: PA004038-PA1356
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Catalog No. PA004038-PA1356
Product NameMCP-1 Polyclonal Antibody
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Synonyms MCP-1/CCL2 Antibody
Isotype Rabbit IgG.
Specificity/Sensitivity Human, rat, mouse. No cross reactivity with other proteins.
Reactivity Human, Rat, Mouse.
Immunogen A synthetic peptide corresponding to a sequence at the N-terminal of human MCP-1 (24-36 aa), different from the mouse sequence by two amino acids.
Purification Immunogen affinity purified.
Form Of Antibody Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg NaN3.
Stability & Storage Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Note Conditions of optimal MCP-1 antibody performance should be determined experimentally by the investigator.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

PA004038-PA1356: MCP-1 Polyclonal Antibody
Background
Monocyte chemoattractant protein-1 (MCP-1), a member of the chemokine (chemotactic cytokine) family, is a potent monocyte agonist that is upregulated by oxidized lipids.1 MCP-1 is also known as CCL2, SCYA2, MCAF. MCAF is a member of family of factors involved in immune and inflammatory responses. The amino acid sequence deduced from the nucleotide sequence reveals the primary structure of the MCAF precursor to be composed of a putative signal peptide sequence of 23 amino acid residues and a mature MCAF sequence of 76 amino acid residues.2 MCP-1 plays a unique and crucial role in the initiation of atherosclerosis and may provide a new therapeutic target in this disorder.3 Human MCP-1 is a 8.7KDa non-glycoprotein, consisting of 99 amino acids in precursor form and 76 amino acids in mature form.
MCP 1 Proteins:
Recombinant Rat MCP-1 (CCL2)
Recombinant Mouse MCP-1 (CCL2)
Recombinant Human MCP-1 (CCL2), His Tag
Recombinant Human MCP-1 (CCL2)

MCP-1 ELISA Kits:
Mouse MCP-1 ELISA Kit
Human MCP-1 ELISA Kit

Additional information

Ship from Country

USA

Size

100 ug

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