MBNL1 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

MBNL1 Rabbit pAb

$108.00$488.00

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$108.00$488.00

EXP; MBNL

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SKU: A8054
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Catalog No. A8054
Product NameMBNL1 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms EXP; MBNL
Gene Name MBNL1
Protein Name MBNL1
Uniprot/Swissprot ID Q9NR56
Entrez GeneID 4154
Clonality Polyclonal
Source/Host Rabbit
Applications WB, IHC-P, IF/ICC
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a member of the muscleblind protein family which was initially described in Drosophila melanogaster. The encoded protein is a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Mice lacking this gene exhibited muscle abnormalities and cataracts. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined. The different isoforms are thought to have different binding specificities and/or splicing activities.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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