[KO Validated] Cyclin D3 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

[KO Validated] Cyclin D3 Rabbit pAb

$128.00$548.00

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$128.00$548.00

CCND3;cyclin D3;Cyclin D3

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SKU: A0746
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Catalog No. A0746
Product Name[KO Validated] Cyclin D3 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms CCND3;cyclin D3;Cyclin D3
Gene Name CCND3
Protein Name CCND3
Uniprot/Swissprot ID P30281
Entrez GeneID 896
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Mouse
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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