KCNN3 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

KCNN3 Rabbit pAb

$108.00$488.00

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$108.00$488.00

SK3; ZLS3; hSK3; SKCA3; KCa2.3

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SKU: A14012
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Catalog No. A14012
Product NameKCNN3 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms SK3; ZLS3; hSK3; SKCA3; KCa2.3
Gene Name KCNN3
Protein Name KCNN3
Uniprot/Swissprot ID Q9UGI6
Entrez GeneID 3782
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
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Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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USA

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20 ul, 100 ul, 200 ul, 50 ul

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