IL13 Rabbit pAb

IL13 Rabbit pAb

$108.00$488.00

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$108.00$488.00

P600; IL-13

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SKU: A1367
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Catalog No. A1367
Product NameIL13 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms P600; IL-13
Gene Name IL13
Protein Name IL13
Uniprot/Swissprot ID P35225
Entrez GeneID 3596
Clonality Polyclonal
Source/Host Rabbit
Applications WB, IF/ICC
Reactivity Human
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul

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