CDX2 Polyclonal Antibody
$250.00 – $350.00
Conditions of optimal CDX2 polyclonal antibody performance should be determined experimentally by the investigator.
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| Catalog No. | PA001142-R12-2609 |
|---|---|
| Product Name | CDX2 Polyclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | caudal type homeo box transcription factor 2; Caudal-type homeobox protein 2; CDX-3; CDX3; Homeobox protein CDX-2 |
| Specificity/Sensitivity | CDX2 antibody detects endogenous levels of CDX2. |
| Reactivity | Human, Mouse, Rat. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human CDX2. |
| Purification | The antibody was affinity-purified from rabbit anti-serum by immunogenic peptide affinity-chromatography. |
| Form Of Antibody | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Stability & Storage | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Note | Conditions of optimal CDX2 antibody performance should be determined experimentally by the investigator. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PA001142-R12-2609: CDX2 Polyclonal Antibody
Introduction
Homeobox protein CDX-2 is a protein that in humans is encoded by the CDX2 gene. The protein encoded by this gene is a homeobox transcription factor. Cdx2 is the gene that directs early embryogenesis in mice. It is required to form the placenta. Ectopic expression of CDX2 was reported more than 85% of the human patients with Acute myeloid leukemia (AML). Ectopic expression of Cdx2 in murine bone marrow induced AML in mice and upregulate Hox genes in bone marrow progenitors.[3][3][4] CDX2 is also implicated in the pathogenesis of Barrett’s esophagus were it has been shown that components from gastroesofageal reflux such as bile acids are able to induce the expression of an intestinal differentiation program through up-regulation of NF-?B and CDX2.
Other CDX2 Antibody:
CDX2 (Ab-283) Polyclonal Antibody
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 50 ug |
