CBR3 Polyclonal Antibody

CBR3 Polyclonal Antibody

$250.00$350.00

In stock

$250.00$350.00

Conditions of optimal CBR3 polyclonal antibody performance should be determined experimentally by the investigator.

SKU: PA001043-C14950
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Catalog No. PA001043-C14950
Product NameCBR3 Polyclonal Antibody
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Synonyms carbonyl reductase 3; EC 1.1.1.184; NADPH-dependent carbonyl reductase 3
Specificity/Sensitivity CBR3 antibody detects endogenous levels of total CBR3 protein.
Reactivity Human, Mouse, Rat.
Immunogen The antiserum was produced against synthesized peptide derived from internal of human CBR3.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form Of Antibody Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol.
Stability & Storage Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing.
Note Conditions of optimal CBR3 antibody performance should be determined experimentally by the investigator.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

PA001043-C14950: CBR3 Polyclonal Antibody
Introduction
CBR3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. CBR3 is one of several monomeric NADPH-dependent oxidoreductases. Furthermore, CBR3 contains 3 exons spanning 11.2 kilobases and is strongly linked to another carbonyl reductase gene, the CBR1. It was suggested that CBR3 mediates 9-cis-retinoic acid-induced cytostatis and is a potential prognostic marker for oral malignancy. CBR3 is identified in the ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and the testis. Polymorphisms in CBR3 may give an explanation to interindividual and interethnic variability of doxorubicin pharmacokinetics and pharmacodynamics.
Other CBR3 Antibody:
CBR3 Monoclonal Antibody

Additional information

Ship from Country

USA

Size

100 ug, 50 ug

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