Bak Polyclonal Antibody
$250.00 – $350.00
Conditions of optimal Bak polyclonal antibody performance should be determined experimentally by the investigator.
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| Catalog No. | PA000900-C0131 |
|---|---|
| Product Name | Bak Polyclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | Bcl-2 homologous antagonist/killer, Apoptosis regulator BAK, Bcl-2-like 7 protein, BAK1, BAK, BCL2L7 |
| Isotype | Human IgG4 kappa. |
| Specificity/Sensitivity | Bak antibody detects endogenous levels of total Bak protein. |
| Reactivity | Human,Mouse. |
| Immunogen | The antiserum was produced against synthesized peptide derived from human Bak. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Form Of Antibody | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Stability & Storage | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Note | Conditions of optimal Bak antibody performance should be determined experimentally by the investigator. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PA000900-C0131: Bak Polyclonal Antibody
Introduction
BAK, officially called Bcl2 antagonist killer, is a protein that in humans, encoded by the BAK gene.The BAK protein is a pro-apoptotic member of the Bcl-2 gene family which is involved in initiating apoptosis. BAK gene spans 7.6 kb and contains 6 exons.By Southern blot analysis of genomic DNA from human/rodent somatic cell hybrids, BAK gene is localized to chromosome 6.This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.
Other Bak Antibody:
BAK Polyclonal Antibody
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 50 ug |
