Anti-p53 WT Unconjugated(102201)
$205.00 – $395.00
Caprico Biotechnologies Anti-p53 WT Unconjugated catalog number:102201,p53 acts as a tumor suppressor in many tumor types; it induces growth arrest or apoptosis depending on the physiological circumstances and cell type.
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Catalog No. | 102201 |
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Product Name | Anti-p53 WT Unconjugated(102201) |
Supplier Name | Caprico Biotechnologies, Inc. |
Brand Name | Caprico |
Accession No. | NM_000546.5 |
Protein Name | p53 |
Uniprot/Swissprot ID | P04637 |
Entrez GeneID | 7157 |
Primary/Secondary | Primary |
Clone | PAB1620 |
Clonality | Monoclonal |
Source/Host | Mouse |
Applications | FC |
Reactivity | Human |
Immunogen | Mouse VLM tumor cells |
Form Of Antibody | PBS pH 7.2, 0.1% (w/v) BSA, 0.09% (w/v) sodium azide |
Conjugate | Unconjugated |
Purity | >95% |
Stability & Storage | 2-8oC |
Note | Products will be shipped from the warehouse in Georgia. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5070 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card. |
Description
102201:Anti-p53 WT Unconjugated(102201)
p53 acts as a tumor suppressor in many tumor types; it induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator, p53 acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
Please remember our product information: Anti-p53 WT Unconjugated(102201) catalog number: 102201 Caprico Biotechnologies
Additional information
Ship from Country | USA |
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Size | 100 μg |