Anti-p53 WT Unconjugated(102201)

Anti-p53 WT Unconjugated(102201) catalog number:102201 Caprico Biotechnologies

Anti-p53 WT Unconjugated(102201)

$205.00$395.00

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$205.00$395.00

Caprico Biotechnologies Anti-p53 WT Unconjugated catalog number:102201,p53 acts as a tumor suppressor in many tumor types; it induces growth arrest or apoptosis depending on the physiological circumstances and cell type.

SKU: 102201
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Catalog No. 102201
Product NameAnti-p53 WT Unconjugated(102201)
Supplier Name Caprico Biotechnologies, Inc.
Brand Name Caprico
Accession No. NM_000546.5
Protein Name p53
Uniprot/Swissprot ID P04637
Entrez GeneID 7157
Primary/Secondary Primary
Clone PAB1620
Clonality Monoclonal
Source/Host Mouse
Applications FC
Reactivity Human
Immunogen Mouse VLM tumor cells
Form Of Antibody PBS pH 7.2, 0.1% (w/v) BSA, 0.09% (w/v) sodium azide
Conjugate Unconjugated
Purity >95%
Stability & Storage 2-8oC
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Description

102201:Anti-p53 WT Unconjugated(102201)

p53 acts as a tumor suppressor in many tumor types; it induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator, p53 acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Implicated in Notch signaling cross-over. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
Please remember our product information: Anti-p53 WT Unconjugated(102201) catalog number: 102201 Caprico Biotechnologies

Additional information

Ship from Country

USA

Size

100 μg

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