SERCA2/ATP2A2 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

SERCA2/ATP2A2 Rabbit pAb

$108.00$488.00

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$108.00$488.00

DD; DAR; ATP2B; SERCA2

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SKU: A0098
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Catalog No. A0098
Product NameSERCA2/ATP2A2 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms DD; DAR; ATP2B; SERCA2
Gene Name ATP2A2
Protein Name ATP2A2
Uniprot/Swissprot ID P16615
Entrez GeneID 488
Clonality Polyclonal
Source/Host Rabbit
Applications WB, IHC-P
Reactivity Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of the skeletal muscle. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Other types of mutations in this gene have been associated with various forms of muscular dystrophies. Alternative splicing results in multiple transcript variants encoding different isoforms.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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