Phospho-MEK2-T394 Rabbit pAb
$218.00 – $548.00
CFC4; MEK2; MKK2; MAPKK2; PRKMK2
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| Catalog No. | AP0121 |
|---|---|
| Product Name | Phospho-MEK2-T394 Rabbit pAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | CFC4; MEK2; MKK2; MAPKK2; PRKMK2 |
| Gene Name | MAP2K2 |
| Protein Name | MAP2K2 |
| Uniprot/Swissprot ID | P36507 |
| Entrez GeneID | 5605 |
| Clonality | Polyclonal |
| Source/Host | Rabbit |
| Applications | WB, IF/ICC |
| Reactivity | Human |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ul, 200 ul, 50 ul |