Phospho-β-Catenin-T41/S45 Rabbit pAb

Phospho-β-Catenin-T41/S45 Rabbit pAb

$128.00$368.00

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$128.00$368.00

EVR7; CTNNB; MRD19; NEDSDV; armadillo

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SKU: AP0336
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Catalog No. AP0336
Product NamePhospho-β-Catenin-T41/S45 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms EVR7; CTNNB; MRD19; NEDSDV; armadillo
Gene Name CTNNB1
Protein Name CTNNB1
Uniprot/Swissprot ID P35222
Entrez GeneID 1499
Clonality Polyclonal
Source/Host Rabbit
Applications WB
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

Additional information

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USA

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20 ul, 100 ul, 50 ul

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