Phospho-Bcl-XL-S62 Rabbit pAb
$218.00 – $548.00
BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S
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| Catalog No. | AP0314 |
|---|---|
| Product Name | Phospho-Bcl-XL-S62 Rabbit pAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | BCLX; BCL2L; Bcl-X; PPP1R52; BCL-XL/S |
| Gene Name | BCL2L1 |
| Protein Name | BCL2L1 |
| Uniprot/Swissprot ID | Q07817 |
| Entrez GeneID | 598 |
| Clonality | Polyclonal |
| Source/Host | Rabbit |
| Applications | WB, IF/ICC |
| Reactivity | Human, Mouse, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ul, 200 ul, 50 ul |