Catalog No.	LGM-MM101
Product Name	Mouse LGMN Protein (LGM-MM101)
Supplier Name	KACTUS Biosystems
Brand Name	KACTUS Biosystems
Synonyms	Legumain; Prsc1; AEP; LGMN; LGMN1; AI746452; AU022324
Species	Mouse
Source	HEK293
Accession	O89017
Product Tag	N-His
Biotinylated	no
Exact Sequence	Val18-Tyr435
Molecular Weight	The protein has a predicted MW of 48.6 kDa. Due to glycosylation, the protein migrates to 55-60 kDa based on Tris-Bis PAGE result.
Form	Liquid
Formulation	Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	Less than 1EU per μg by the LAL method.
Shipping	Shipped with dry ice.
Stability & Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

LGM-MM101: Mouse LGMN Protein (LGM-MM101)

Recently, functional studies have demonstrated that legumain (LGMN) cleaves both amyloid β-protein precursor and tau, promoting senile plaques and formation of neurofibrillary tangles, which may play a crucial role in the pathogenesis of Alzheimer’s disease (AD). In single-variant association analysis, none of the common variants in LGMN were statistically significant. In gene-based analysis, the LGMN gene also showed no association with AD.

Please remember our product information: Mouse LGMN Protein (LGM-MM101) catalog number: LGM-MM101 KACTUS Biosystems

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