Mouse CRTAM Protein (CRM-MM101)
$216.00 – $720.00
KACTUS Biosystems Mouse CRTAM Protein (CRM-MM101) (catalog No. CRM-MM101) is expressed from HEK293 with His tag at the C-Terminus.It contains Ala17-Gly289.
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| Catalog No. | CRM-MM101 |
|---|---|
| Product Name | Mouse CRTAM Protein (CRM-MM101) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | CD355 antigen; CD355; CRTAM |
| Species | Mouse |
| Source | HEK293 |
| Accession | Q149L7-1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Ala17-Gly289 |
| Molecular Weight | The protein has a predicted MW of 31.1 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
CRM-MM101: Mouse CRTAM Protein (CRM-MM101)
Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.
Please remember our product information: Mouse CRTAM Protein (CRM-MM101) catalog number: CRM-MM101 KACTUS Biosystems