[KO Validated] RB Rabbit pAb
$128.00 – $548.00
RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1
SKU: A0003
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| Catalog No. | A0003 |
|---|---|
| Product Name | [KO Validated] RB Rabbit pAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1 |
| Gene Name | RB1 |
| Protein Name | RB1 |
| Uniprot/Swissprot ID | P06400 |
| Entrez GeneID | 5925 |
| Clonality | Polyclonal |
| Source/Host | Rabbit |
| Applications | WB, IF/ICC |
| Reactivity | Human |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 20 ul, 100 ul, 200 ul, 50 ul |
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