Fbx32/FBOX32 Rabbit pAb

Fbx32/FBOX32 Rabbit pAb

$108.00$488.00

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$108.00$488.00

Fbx32; MAFbx

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SKU: A6825
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Catalog No. A6825
Product NameFbx32/FBOX32 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms Fbx32; MAFbx
Gene Name FBXO32
Protein Name FBXO32
Uniprot/Swissprot ID Q969P5
Entrez GeneID 114907
Clonality Polyclonal
Source/Host Rabbit
Applications WB, IF/ICC
Reactivity Human, Mouse
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

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USA

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20 ul, 100 ul, 200 ul

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