CD215/IL-15R alpha Rabbit pAb

CD215/IL-15R alpha Rabbit pAb

$108.00$488.00

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$108.00$488.00

CD215

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SKU: A2983
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Catalog No. A2983
Product NameCD215/IL-15R alpha Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms CD215
Gene Name IL15RA
Protein Name IL15RA
Uniprot/Swissprot ID Q13261
Entrez GeneID 3601
Clonality Polyclonal
Source/Host Rabbit
Applications WB, IF/ICC
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul

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