Price/availability/specifications subject to change without notice. Unless otherwise indicated, our catalog and customized products are for research use only and not intended for human or animal diagnostic or therapeutic use.
Or leave a message with a formal purchase order (PO) Or credit card.
Cas9 Nuclease is a double-strand DNA endonuclease that uses a single guide RNA (sgRNA) to specify the site of cleavage.
Cas9 Nuclease is a double-strand DNA endonuclease that uses a single guide RNA (sgRNA) to specify the site of cleavage. sgRNA contains complementary region for specific DNA binding, and can lead the Cas9 Nuclease to the target DNA. Cas9 Nuclease contains two nuclease domains, which can cut each strand of DNA duplex to produce double strand break. The cutting site locates at 3 bp from NGGPAM of the complementary region of target DNA.