CAMLG Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

CAMLG Rabbit pAb

$108.00$488.00

In stock

$108.00$488.00

CAML; GET2; CDG2Z

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SKU: A13720
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Catalog No. A13720
Product NameCAMLG Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms CAML; GET2; CDG2Z
Gene Name CAMLG
Protein Name CAMLG
Uniprot/Swissprot ID P49069
Entrez GeneID 819
Clonality Polyclonal
Source/Host Rabbit
Applications WB, IHC-P, IF/ICC
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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