Biotinylated Recombinant Human ACE2

Source
Biotinylated Recombinant human ACE2 is expressed from mammalian with a His tag and Avi at the C-terminal.    
It contains Gln18- Ser740.

Accession
Q9BYF1

Molecular Weight
The protein has a predicted MW of 86.5kDa. Due to glycosylation, the protein migrates to 95-110KDa based on Bis-Tris PAGE result.

Endotoxin
Less than 1EU per ug by the LAL method.

Purity
> 95% as determined by Bis-Tris PAGE   
> 95% as determined by HPLC

Formulation
Lyophilized from 0.22um filtered solution in 20mM PB (pH 7.4). Normally 5 % trehalose is added as protectant before lyophilization.

Storage
The product should be stored at -70℃ or -20℃.

Background
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7.