Anti-mouse CD11c Monoclonal Antibody (Clone: N418), Hamster IgG2 Kappa, In vivo Grade Recombinant

Catalog No.	PA007390.hs2
Product Name	Anti-mouse CD11c Monoclonal Antibody (Clone: N418), Hamster IgG2 Kappa, In vivo Grade Recombinant
Supplier Name	Syd Labs, Inc.
Brand Name	Syd Labs
Synonyms	αX integrin, CR4, p150, integrin alpha X
Summary	The in vivo Grade Recombinant Anti-mouse CD11c Monoclonal Antibody, Hamster IgG2 Kappa (Clone: N418) was produced in mammalian cells.
Clone	N418
Isotype	Hamster IgG2 kappa
Specificity/Sensitivity	The in vivo grade recombinant hamster monoclonal antibody (clone: N418) specifically binds to mouse CD11c.
Applications	ELISA, flow cytometry, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by the mouse CD11c protein.
Form Of Antibody	0.2 μM filtered solution of 1x PBS.
Endotoxin	< 1 EU per 1 mg of the protein by the LAL method.
Purity	>95% by SDS-PAGE under reducing conditions.
Shipping	The in vivo grade recombinant anti-mouse CD11c antibodies (clone of N418) are shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
Note	Recombinant hamster IgG2 isotype controls are available. Condition of sample preparation and optimal sample dilution should be determined experimentally by the investigator.
Order Offline	Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card.

Description

PA007156.mf

PA007390.hs2: In vivo Grade Recombinant Anti-mouse CD11c Monoclonal Antibody, Hamster IgG2 Kappa (Clone: N418)

The in vivo grade recombinant anti-mouse CD11c hamster IgG2 monoclonal antibody was produced in mammalian cells.

Background

The hamster anti-mouse CD11c monoclonal antibody N418 (hamster IgG2 kappa) reacts with the mouse CD11c protein, the most widely used defining marker for dendritic cells (DCs). The CD11c protein helps cells stick together and is involved in many processes, including phagocytosis, cell migration, and the activation of T cells. CD11c helps cells stick together by binding to molecules like ICAM-1, fibrinogen, and iC3b, helps cells engulf and digest other cells, helps Langerhans cells activate T cells, regulates neutrophil maturation and function, and helps dendritic cells capture and activate other cells. In addition to dendritic cells and tissue macrophages, CD11c is expressed in different B-cell lymphomas, including chronic lymphocytic leukemia. CD11c-expressing cells are also found in the mouse nervous system.

Our recombinant N418 antibodies have a part (variable regions) or complete amino acid sequences of the hamster anti-mouse CD11c monoclonal antibody (hybridoma clone name or number: N418).

Related Recombinant IgG Reference Antibodies:

In vivo grade recombinant hamster IgG2 isotype control antibody

Please remember our product information: In vivo Grade Recombinant Anti-mouse CD11c Monoclonal Antibody, Hamster IgG2 Kappa (Clone: N418): PA007390.hs2 Syd Labs

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