AMPKα2 Rabbit pAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

AMPKα2 Rabbit pAb

$108.00$488.00

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$108.00$488.00

AMPK; AMPK2; PRKAA; AMPKa2

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SKU: A0791
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Catalog No. A0791
Product NameAMPKα2 Rabbit pAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms AMPK; AMPK2; PRKAA; AMPKa2
Gene Name PRKAA2
Protein Name PRKAA2
Uniprot/Swissprot ID P54646
Entrez GeneID 5563
Clonality Polyclonal
Source/Host Rabbit
Applications WB, IF/ICC
Reactivity Human,Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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